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polymeric micelles with sorafenib and SPION

Based on

1 Articles
2013 Most recent source

Composition

1

polycaprolactone

PCL
Type Polymer
Formula
Role core
2

superparamagnetic iron oxide nanoparticles

SPION SPIO
Type Nano Material
Formula
Role loaded material
3

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role layer
4

poly(ethylene glycol)

poly(ethylene oxide) polyethylene glycol polyethylene oxide polyoxyethylene PEG PEO POE
Type Polymer
Formula
Role layer
5

folate acid

folic acid folate FOL FA
Type Single Compound
Formula C19H19N7O6
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
relaxivity

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
hepatic carcinoma HepG2 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. 0OCFW3zEhWV8j
  2. MQ6FXZZ46eLuXt0TVeZ
Product

polymeric micelles with sorafenib and SPION

Hydrodynamic diameter: 77 - 83 nm

Medium: water

Support: none

References

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