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methotrexate-loaded PEI/mPEG-COOH nano-network particles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

polyethyleneimine-dithiodipropionic acid cross-linking

PEI-DTDP
Type Polymer
Formula
Role core
2

mPEG-COOH

Type Polymer
Formula
Role layer
3

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material

Properties

General physical and chemical properties

Property Value Source
methotrexate release dependent on pH

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
atomic force microscopy

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Biological effects

Biological system Test details Source
human hepatocellular carcinoma cells (HepG2)

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Preparation

Method 1

Type: Physical formation
Source:
Product

methotrexate-loaded PEI/mPEG-COOH nano-network particles

Method 2

Type: Physical formation
Source:
Product

methotrexate-loaded PEI/mPEG-COOH nano-network particles

References

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