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arginine-based cationic liposome-pDNA complexes

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

1,5-ditetradecyl-N-arginyl-N-trityl-L-glutamate NH3+TFA- salt form

arginine-based cationic lipid
Type Single Compound
Formula C47H86F6N6O10
Role layer
3

deoxyribonucleic acid

pGL4.75[hRluc/CMV] DNA
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
HeLa human cervical cancer cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

arginine-based cationic liposome-pDNA complexes

Hydrodynamic diameter: ~ 170 - ~ 250 nm

Medium: Dulbecco's modified Eagle medium with serum

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

arginine-based cationic liposome-pDNA complexes

Hydrodynamic diameter: ~ 150 - ~ 600 nm

Medium: Dulbecco's modified Eagle medium

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  1. aA4FvanjCJ5qV9ERY7QdEHATQd
  2. VRACWW
Product

arginine-based cationic liposome-pDNA complexes

Size: not specified

Medium/Support: none

References

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