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FCPC/DNA complexes

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

chitosan-graft-branched polyethylenimine

chitosan-graft-PEI CHI-g-PEI
Type Polymer
Formula
Role raw materials
2

folated poly(ethylene glycol)

folate-PEG Fol-PEG
Type Polymer
Formula
Role graft
3

programmed cell death 4 gene

deoxyribonucleic acid Pdcd4 gene DNA
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability during DNase I enzyme degradation

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
H-ras12V transgenic mouse with liver cancer

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • folated poly(ethylene glycol)
  1. 2KsGlKzI8nN5FXvC39XSLbiK7YJZL
  2. c10iGAjiTSoc91TNLKdP1v8yIbhxRq95vv2g4bVlzHwSV3UjyAiUnjwBz311Ekxo2Up432B8QheFUdlLelAb1cNw3gvM7SWkhoq1R0ojuDwlAShNND5rJk
Product

FCPC/DNA complexes

Hydrodynamic size: ~ 58 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • folated poly(ethylene glycol)
  1. zfBUEb6kS8Xr3o1jRQpBNrDxn7Gkm
  2. owBxGNoKzR1sMHcPEtApbgbj2hEG6OHPXtCfs5Q8bV84Ol5uK2WtU8JpBTUhY9X7TkOWXSqcnlaL0H4yUZJU2rf45aYVpxroKmaCfWfhoyTFEFdxhcqfR3
Product

FCPC/DNA complexes

Hydrodynamic size: ~ 65 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • folated poly(ethylene glycol)
  1. aEtLhpaZHmKgXlWb77LHHFUwNLERk
  2. CD6syYmPGcpJd6wj6GskhnsmYyUTGSpbn2rGr8TqiJjDzygNiJwFt1Q7HtHWEEhOhvnEf4jqCCKj0ztFI3TSZwxA3pF8JG1OUQC6QLN0AtjK6MYA1x1Nxg
Product

FCPC/DNA complexes

Hydrodynamic size: ~ 70 nm

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • folated poly(ethylene glycol)
  1. gflkkJt96wetrfubgs9qg5kbnRUxo
  2. ZvYAhmYIPWG9QR20hPDyS91nwYx8CQDvUdVVVL1vDLMuz6NjkRDJ5j52bHkkHzY703RqsPAIegExylrZSa566KWim9mkWhbG7N7jznVYxOqpjYvipuqT6R
Product

FCPC/DNA complexes

Hydrodynamic size: ~ 55 nm

Size: 39.4 - 76.0 nm

Medium/Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • folated poly(ethylene glycol)
  1. GCH40UvTyJwsd6qM4s65Rx56v7W3P
  2. dGBFaDNtzqeU2Kirvd6hnjGSJQsYW2gaFqbhTy65CxTh7QkGQLqGAoJKuHXlHTNSTrI5hg87ZqWszeQV99sanFJc5jw61pH4IFtlmGkwTbWZIEAoVcRxBB
Product

FCPC/DNA complexes

Size: not specified

Medium/Support: none

References

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