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RGD peptide-grafted PEG-based liposomes

Based on

1 Articles
2013 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

mixture of substance based on (N-carbonyl-methoxy-(polyethyleneglycol 2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine sodium salt/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol-2000)] ammonium salt/soy lecithin)

Type Complex Compound
Formula
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
4

arginine-glycine-aspartic acid-D-phenylalanine-cysteine cyclic peptide

cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-L-cysteinyl) Arg-Gly-Asp-D-Phe-Cys cyclic pentapeptide cyclic Arg-Gly-Asp polypeptide cyclo(Arg-Gly-Asp-D-Phe-Cys) cyclic RGD polypeptide RGD peptide cyclic RGD cRGDfC cRGD RGD
Type Single Compound
Formula C24H34N8O7S
Role graft

Properties

Applications

Area Application Source
drug delivery

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
human neuroblastoma Kelly cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. xsRK3AA5pYBkeovzyB3ohCJsAGp
  2. R5Ofth
  3. DP40QO4c
Product

RGD peptide-grafted PEG-based liposomes

References

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