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PLGA nanoparticles

Based on

3 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

polyethylene glycol-poly(2-(diisopropylamino)ethyl methacrylate) diblock copolymer

PEG113-b-PDPA46 PEG-b-PDPA
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
female Balb/c mouse bearing MCF-7/ADR tumor xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polyethylene glycol-poly(2-(diisopropylamino)ethyl methacrylate) diblock copolymer
  • poly(lactic-co-glycolic acid)
  1. S10KTr3RqCzBzEAlGlLpL
  2. vsIT6b8FA3buB55y
Product

PLGA nanoparticles

Diameter: ~ 20 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • Pluronic F-68
  • poly(lactic-co-glycolic acid)
  • water
  1. urOzPNz7o22F4QOBZgiCaa12E7IURvJflwhT85xHjsttvqr9aD1JGdYzlRF62nNPTzU7DQ
Product

PLGA nanoparticles

Hydrodynamic diameter: 213 - 251 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • Pluronic F-68
  • poly(lactic-co-glycolic acid)
  • water
  1. BatJwAL43IaVxHYW7BjL97HTVYUydF7ugXRBId9nA7OknPXH8QlhGBgUq7jOzP0y99vm3Akh
Product

PLGA nanoparticles

Hydrodynamic diameter: 266 - 332 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • polyethylene glycol-poly(2-(diisopropylamino)ethyl methacrylate) diblock copolymer
  1. Xz29NVYJHxpbclf9XoBBn
  2. bZduhY1u4fBtd224
Product

PLGA nanoparticles

Diameter: ~ 20 nm

Hydrodynamic diameter: ~ 50 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • Pluronic F-68
  • poly(lactic-co-glycolic acid)
  • water
  1. lfdKGulWUkIgs3NdbkfoQNWJvFgVoiEsnLF9BDS780iRZUNZ903IRw7uwoYvVqLJn2eDBtC
Product

PLGA nanoparticles

Hydrodynamic diameter: 440 - 522 nm

Medium: water

Support: none

References

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