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pH-responsive nanoparticles with bafilomycin A1

Based on

1 Articles
2012 Most recent source

Composition

1

Cy5-labeled pEGFP

Cy5-labeled DNA DNA-Cy5
Type Biomolecule
Formula
Role core
2

dual pH-responsive random copolymer

poly-β-aminoester ketal-2
Type Polymer
Formula
Role layer
3

2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride

2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride tris(hydroxymethyl)aminomethane hydrochloride tris-hydroxymethyl aminomethane hydrochloride Tris hydrochloride Tris HCl Tris*HCl Tris-HCl
Type Single Compound
Formula C4H12ClNO3
Role loaded material
4

trethalose

trehalose
Type Single Compound
Formula C12H22O11
Role loaded material
5

bafilomycin A1

Type Single Compound
Formula C35H58O9
Role loaded material

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
HCT116 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride
  • Cy5-labeled pEGFP
  • dual pH-responsive random copolymer
  1. s7N
  2. izyr
  3. E0y
Product

pH-responsive nanoparticles with bafilomycin A1

Hydrodynamic diameter: ~ 300 nm

Medium/Support: none

References

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