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docetaxel-loaded soybean lecithin/Solutol® HS 15-stabilized MCT/Brucea javanica oil nanodroplets in PEG 400 water solution

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

docetaxel/medium-chain triglyceride/Brucea javanica oil mixture

DTX/MCT/Brucea javanica oil mixture
Type Complex Compound
Formula
Role core
2

soybean lecithin/Solutol® HS 15 mixture

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Sprague Dawley rat

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • Brucea javanica oil
  • n-octanoic acid
Product

docetaxel-loaded soybean lecithin/Solutol® HS 15-stabilized MCT/Brucea javanica oil nanodroplets in PEG 400 water solution

Hydrodynamic diameter: 13.5 nm

Medium: 5 % PEG 400 water solution

Support: none

References

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