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sirolimus solid-dispersion nanoparticles

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

polyvinylpyrrolidone K30

PVP K30
Type Polymer
Formula
Role core
2

rapamycin

sirolimus RAPA RAP SR
Type Single Compound
Formula C51H79NO13
Role loaded material
3

sucrose monopalmitate

Sucroester 15 SE 15
Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
dissolution

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
Sprague-Dawley rat

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polyvinylpyrrolidone K30
  • sucrose monopalmitate
  • rapamycin
  1. ipYKwqLfLlZnpQACWlF5
  2. tsJbVzKAtOsaQ2EKhw2qTEb6IAwM
Product

sirolimus solid-dispersion nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. izO7M2j9fy
Product

sirolimus solid-dispersion nanoparticles

Hydrodynamic diameter: 200 - 404 nm

Medium: mineral oil

Support: none

References

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