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celecoxib-loaded poly(lactic-co-glycolic acid) nanoparticles

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role raw materials
2

4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide

celecoxib celebrex CEB CEL CLX
Type Single Compound
Formula C17H14F3N3O2S
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
brain tumor U87MG cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • poly(lactic-co-glycolic acid)
  1. T1dV28VB3r5SvPse
Product

celecoxib-loaded poly(lactic-co-glycolic acid) nanoparticles

Hydrodynamic diameter: 41 - 169 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • poly(lactic-co-glycolic acid)
  1. XuGHsw8A9cpMmh3
Product

celecoxib-loaded poly(lactic-co-glycolic acid) nanoparticles

Hydrodynamic diameter: 192.0 - 319.0 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • poly(lactic-co-glycolic acid)
  1. 22j9pHiTh6EH5c1
Product

celecoxib-loaded poly(lactic-co-glycolic acid) nanoparticles

Hydrodynamic diameter: 82.5 - 147.7 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • poly(lactic-co-glycolic acid)
  1. 9VOXfk0c1ePwVl5a72v
Product

celecoxib-loaded poly(lactic-co-glycolic acid) nanoparticles

Hydrodynamic diameter: 113.4 - 231.6 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • poly(lactic-co-glycolic acid)
  1. O0ayAu4oNsIIEd0QyVr
Product

celecoxib-loaded poly(lactic-co-glycolic acid) nanoparticles

Hydrodynamic diameter: 81.3 - 153.5 nm

Medium: water

Support: none

References

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