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sirolimus solid-dispersion nanoparticles

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

polyvinylpyrrolidone K30

PVP K30
Type Polymer
Formula
Role core
2

sirolimus

sirolimus RAPA RAP SR
Type Single Compound
Formula C51H79NO13
Role loaded material
3

stearoyl macrogol glyceride

Gelucire 50/13
Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
kinetic solubility

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Applications

Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
Sprague-Dawley rat

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • sirolimus
  • polyvinylpyrrolidone K30
  • stearoyl macrogol glyceride
  1. HTgpwu2LfVb7awxmIRy7
  2. wMDpr0XbOfPUMeWV0a002OgYG7X6
Product

sirolimus solid-dispersion nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. WiXWwZiFf0
Product

sirolimus solid-dispersion nanoparticles

Hydrodynamic diameter: 358 - 548 nm

Medium: mineral oil

Support: none

References

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