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didodecyl dimethylammonium bromide modified coumarin-6 loaded poly(lactide-co-glycolide) nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

N-dodecyl-N,N-dimethyldodecan-1-aminium bromide

dodecyl-N,N-dimethyl-1-dodecanaminium bromide didodecyl dimethylammonium bromide didodecyldimethylammonium bromide dimethyldidodecylammonium bromide dilauryldimethylammonium bromide dDDdMABr DDAB DMAB
Type Single Compound
Formula C26H56BrN
Role layer
3

3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one

3-(2-benzothiazolyl)-N,N-diethylumbelliferylamine 3-(2-benzothiazolyl)-7-(diethylamino)coumarin 6-coumarin coumarin 6 coumarin-6 C6 dye Cou6 C-6
Type Single Compound
Formula C20H18N2O2S
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
heterogeneous human epithelial colorectal adenocarcinoma Caco-2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
  • N-dodecyl-N,N-dimethyldodecan-1-aminium bromide
  • poly(lactic-co-glycolic acid)
  1. kJY0hOJ6F5qFTMe4ns3DkYB5egbWLW
  2. TAH5LYtSX4hU5HCOoa7Vlq
Product

didodecyl dimethylammonium bromide modified coumarin-6 loaded poly(lactide-co-glycolide) nanoparticles

Hydrodynamic diameter: 179.1 - 215.9 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
  • N-dodecyl-N,N-dimethyldodecan-1-aminium bromide
  • poly(lactic-co-glycolic acid)
  1. pwTdN47wInEFA9S2C0J5Sds5kqMx76
  2. H1HMct1GBWoc9I45lPuH0y
Product

didodecyl dimethylammonium bromide modified coumarin-6 loaded poly(lactide-co-glycolide) nanoparticles

Hydrodynamic diameter: 85.2 - 122.0 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Product

didodecyl dimethylammonium bromide modified coumarin-6 loaded poly(lactide-co-glycolide) nanoparticles

Size: ~ 50 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
  • N-dodecyl-N,N-dimethyldodecan-1-aminium bromide
  • poly(lactic-co-glycolic acid)
  1. QcmmMVvKvHcY3EcJ5PDuT5jisK9kVJ
  2. qwevvP4dJTgcUYGM5qKfMB
Product

didodecyl dimethylammonium bromide modified coumarin-6 loaded poly(lactide-co-glycolide) nanoparticles

Hydrodynamic diameter: 130.2 - 163.8 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Product

didodecyl dimethylammonium bromide modified coumarin-6 loaded poly(lactide-co-glycolide) nanoparticles

Size: ~ 100 nm

Medium/Support: none

References

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