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siRNA-loaded RGD-PEGylated nanoliposomes

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

small interfering RNA

siRNA
Type Biomolecule
Formula
Role loaded material
3

DC-cholesterol/DOPE/DSPE-PEG(2000)-RGD lipid mixture

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Characterization

Method Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (1,2-dioleoyl-sn-glycero-3- phosphoethanolamine)
  • 3β-(N-(N',N'-dimethylaminoethane)carbamoyl)cholesterol
  • RGD peptide-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]-maleimide
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Product

siRNA-loaded RGD-PEGylated nanoliposomes

Method 2

Type: Physical formation
Source:
Starting materials
  • (1,2-dioleoyl-sn-glycero-3- phosphoethanolamine)
  • 3β-(N-(N',N'-dimethylaminoethane)carbamoyl)cholesterol
  • RGD peptide-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]-maleimide
  1. JiiLnjOTRX2elcCVMkmvCD
  2. doPs727tDV6k5cCbIsT
  3. jmduxQbBvh4LlnRfRUlW8q
Product

siRNA-loaded RGD-PEGylated nanoliposomes

References

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