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siRNA-loaded RGD-PEGylated nanoliposomes

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

small interfering RNA

siRNA
Type Biomolecule
Formula
Role loaded material
3

DC-cholesterol/DOPE/DSPE-PEG(2000)-carboxy lipid mixture

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human retinal pigment epithelial ARPE-19 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

siRNA-loaded RGD-PEGylated nanoliposomes

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

siRNA-loaded RGD-PEGylated nanoliposomes

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

siRNA-loaded RGD-PEGylated nanoliposomes

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]
  • (1,2-dioleoyl-sn-glycero-3- phosphoethanolamine)
  • 3β-(N-(N',N'-dimethylaminoethane)carbamoyl)cholesterol
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  3. ucvQzVNRPCAMXRmIlqYJnD
Product

siRNA-loaded RGD-PEGylated nanoliposomes

Hydrodynamic diameter: 99.0 - 195.4 nm

Medium: phosphate buffer solution

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • (1,2-dioleoyl-sn-glycero-3- phosphoethanolamine)
  • 3β-(N-(N',N'-dimethylaminoethane)carbamoyl)cholesterol
  • RGD peptide-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]-maleimide
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  2. YWnkpGDUCprTuki8TIA
  3. J3k7ps0TuFuERtqXptbPeI
Product

siRNA-loaded RGD-PEGylated nanoliposomes

Hydrodynamic diameter: 118.9 - 193.9 nm

Medium: phosphate buffer solution

Support: none

References

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