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tamoxifen citrate-loaded microemulsion in phosphatidylcholine

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

ethanol/water

Type Complex Compound
Formula
Role core
2

tamoxifen citrate

Type Single Compound
Formula C32H37NO8
Role loaded material
3

polyoxyethylene (20) sorbitan monooleate

Polysorbate 80 Alkest TW 80 Tween 80
Type Polymer
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
MCF-7 breast cancer cell

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • ethanol
  • water
See all (4)
  1. Vi91RPLAcOrD0wsH
Product

tamoxifen citrate-loaded microemulsion in phosphatidylcholine

Droplet size: 6.04 nm

Medium: [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • ethanol
  • water
See all (4)
  1. 3TqwBYvj22S3BBhv
Product

tamoxifen citrate-loaded microemulsion in phosphatidylcholine

Droplet size: 9.62 nm

Medium: [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • ethanol
  • water
See all (4)
  1. O5NmyS7BzrdhH3HS
Product

tamoxifen citrate-loaded microemulsion in phosphatidylcholine

Droplet size: 6.04 nm

Medium: [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • ethanol
  • water
See all (4)
  1. MgthaWHdpu8eMCsS
Product

tamoxifen citrate-loaded microemulsion in phosphatidylcholine

Droplet size: 4.97 nm

Medium: [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • ethanol
  • water
See all (4)
  1. R4dPZtSKwyiKTyiX
Product

tamoxifen citrate-loaded microemulsion in phosphatidylcholine

Droplet size: 8.33 nm

Medium: [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

Support: none

References

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