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mitoxantrone-loaded liposomes

Based on

1 Articles
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione

1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino) ethylamino]-anthracene-9,10-dione mitoxantrone mitox MTO MTX Mit
Type Single Compound
Formula C22H28N4O6
Role loaded material
3

1,2-dipalmitoyl-sn-glycero-phosphatidylcholine

dipalmitoyl phosphatidylcholine dipalmitoylphosphatidylcholine DPPC
Type Single Compound
Formula C40H80NO8P
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on pH

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Applications

Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
human breast cancer MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
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Product

mitoxantrone-loaded liposomes

References

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