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gemcitabine-loaded chitosan-Pluronic® F-127 nanoparticles

Based on

2 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

chitosan-Pluronic® F-127

Type Complex Compound
Formula
Role carriers
2

2',2'-difluorodeoxycytidine

gemcitabine
Type Single Compound
Formula C9H11F2N3O4
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on Pluronic F127 concentration

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
colon carcinoma HT-29 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • chitosan
  • Pluronic® F127
  1. u4zcMUxa4kGxuzuLyCdh3xlPJTsK
Product

gemcitabine-loaded chitosan-Pluronic® F-127 nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • chitosan
  • Pluronic® F127
  1. eUU6FHrLdUHnryB80cmXekXIuKCC
Product

gemcitabine-loaded chitosan-Pluronic® F-127 nanoparticles

Diameter: 98.16 - 105.84 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • chitosan
  • Pluronic® F127
  1. I5qnMhfob7NDn29xeoVywD7TxXX0
Product

gemcitabine-loaded chitosan-Pluronic® F-127 nanoparticles

Diameter: 107.72 - 114.28 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

gemcitabine-loaded chitosan-Pluronic® F-127 nanoparticles

Size: not specified

Medium: phosphate buffered saline

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • chitosan
  • Pluronic® F127
  1. T9G7x8K8EJkKJ73Wi3qQeUgRAoeJ
Product

gemcitabine-loaded chitosan-Pluronic® F-127 nanoparticles

Diameter: 102.8 - 115.2 nm

Medium: water

Support: none

References

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