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chitosan-siRNA nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

low molecular weight chitosan

Type Biomolecule
Formula
Role carriers
2

Sjogren syndrome antigen-targeted siRNA

SSB siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
suspension stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cervical carcinoma HeLa cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. gUWohtcAEQ8DXtZNjN21
  2. W77emMWu4h6
Product

chitosan-siRNA nanoparticles

Size: ~ 161.1 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. 8ad7KKWXwDpwYn6VP04T
  2. d328wp4xMMO
Product

chitosan-siRNA nanoparticles

Size: ~ 168 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. lQtYazd0MjTIr48PB87t
  2. paUJWYjPxYl
Product

chitosan-siRNA nanoparticles

Size: 116.7 - 124.3 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. r08zrnEorMlghtG0EElS
  2. kcTEhp9a3yZ
Product

chitosan-siRNA nanoparticles

Size: ~ 176 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • low molecular weight chitosan
  1. ZbY0DB8A7wPPz4MXA4ul
  2. jnaGEgUP0d2
Product

chitosan-siRNA nanoparticles

Size: 202.5 - 212.9 nm

Medium: 5 mM acetate buffer/4.3 mM sodium sulfite buffer mixture

Support: none

References

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