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FAM-siRNA-loaded RGD-PEGylated nanoliposomes

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

FAM-labeled small interfering RNA

FAM-labeled siRNA
Type Biomolecule
Formula
Role loaded material
3

DC-cholesterol/DOPE/DSPE-PEG(2000)-RGD lipid mixture

Type Complex Compound
Formula
Role layer

Properties

Applications

Characterization

Biological effects

Biological system Test details Source
human retinal pigment epithelial ARPE-19 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (1,2-dioleoyl-sn-glycero-3- phosphoethanolamine)
  • 3β-(N-(N',N'-dimethylaminoethane)carbamoyl)cholesterol
  • RGD peptide-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]-maleimide
  1. reR2a0fFQLWVTaThC2QHyQ
  2. KCV8x4GC0SrQvfgwSPL
  3. 9aepusenCDTFG9jcirbpVD
Product

FAM-siRNA-loaded RGD-PEGylated nanoliposomes

Method 2

Type: Physical formation
Source:
Starting materials
  • (1,2-dioleoyl-sn-glycero-3- phosphoethanolamine)
  • 3β-(N-(N',N'-dimethylaminoethane)carbamoyl)cholesterol
  • RGD peptide-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000]-maleimide
  1. bmuNjpVa18HcKYcXY9q1Th
  2. K6rVh0i00rHMDsKMNiA
  3. EhvFD3aEIygfZ8tRkFDQXd
Product

FAM-siRNA-loaded RGD-PEGylated nanoliposomes

References

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