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MTM SDK-loaded PEG-p(Asp-Hyd) block copolymer micelles

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethylene glycol)-poly(L-aspartate hydrazide) block copolymer

PEG-p(Asp-Hyd) block copolymer
Type Polymer
Formula
Role raw materials
2

3-side-chain-modified mithramycin

MTM SDK
Type Single Compound
Formula C50H70O24
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human nonsmall cell lung cancer A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

MTM SDK-loaded PEG-p(Asp-Hyd) block copolymer micelles

Hydrodynamic diameter: 9.42 - 14.96 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-poly(L-aspartate hydrazide) block copolymer
  • 3-side-chain-modified mithramycin
  1. zRAoxmC7uMzy9Pxw
Product

MTM SDK-loaded PEG-p(Asp-Hyd) block copolymer micelles

Size: not specified

Medium/Support: none

References

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