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clodronate-loaded poly(lactic-co-glycolic acid) nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

aqueous solution

Type Complex Compound
Formula
Role core
2

(dichloro-phosphono-methyl)phosphonic acid disodium salt

sodium clodronate clodronate
Type Single Compound
Formula CH2Cl2Na2O6P2
Role loaded material
3

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human skin fibroblast CCL-110 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

clodronate-loaded poly(lactic-co-glycolic acid) nanoparticles

Hydrodynamic diameter: 217 - 223 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (dichloro-phosphono-methyl)phosphonic acid disodium salt
  • poly(lactic-co-glycolic acid)
  • water
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Product

clodronate-loaded poly(lactic-co-glycolic acid) nanoparticles

Size: not specified

Medium/Support: none

References

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