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lipid-coated poly(lactic acid-co-glycolic acid)/siRNA nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

1

small interfering RNA

si-RNA
Type Biomolecule
Formula
Role core
2

poly(lactide-co-glycolide)

PLGA
Type Polymer
Formula
Role layer
3

DOTAP/DOPE

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
DU145 (human prostate cancer)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactide-co-glycolide)
  • KIF11
  1. FzbaBLsz9GMZD0FEa8mwhr7EZyaut7hv2J
  2. rGIiCj8cIHYXFJDBbxaRW67A0rgtv0xEJPXPWV7caILd9x
Product

lipid-coated poly(lactic acid-co-glycolic acid)/siRNA nanoparticles

Diameter: 80 nm

Hydrodynamic diameter: 203.339 - 211.461 nm

Length: 320 nm

Medium/Support: none

References

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