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methotrexate-glycine-glycine conjugated O,N-carboxymethyl chitosan nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

methotrexate-glycine-glycine conjugated O,N-carboxymethyl chitosan

O,N-CMCS-Gly-Gly-MTX
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human myeloma RPMI 8226 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • O-carboxymethylated chitosan
  1. DFct0DdLzmucR4M41Ahm3ZxbADK2DATjf5ebTH4W6wfjIYgHKvfcCPgLoKYBaXlzNIwixTxguqRq2tcwB6fTSNp5kHSHz5AVSV0uA
  2. C3YKZyrnFfWX8Hra
  3. FsF
Product

methotrexate-glycine-glycine conjugated O,N-carboxymethyl chitosan nanoparticles

Hydrodynamic diameter: 109 - 127 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • O-carboxymethylated chitosan
  1. L3EUWowO4CM1sefBqfQLrrKGkstzoVEzGhBLd82CDglI6qeYrf2nu3oR1tDn6yLF70dqzt2b8rGlOOFj0vmsNEwppm2PQwKJbXzyw
  2. cO7hW9gQxLETukFP
  3. aWQ
Product

methotrexate-glycine-glycine conjugated O,N-carboxymethyl chitosan nanoparticles

Hydrodynamic diameter: 104 - 114 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • O-carboxymethylated chitosan
  1. aYE6s2yStFCyUrmamTX0XXeA3YuBatrZBnfClFPS3pDScVBMn9I6dVPwVAUlT5eJnnPoPhk4mODmQUNa7HAY29nnUXc2zgCufjoZ9
  2. hdFJm8AVWLWBmWod
  3. VCp
Product

methotrexate-glycine-glycine conjugated O,N-carboxymethyl chitosan nanoparticles

Hydrodynamic diameter: 114 - 122 nm

Medium: phosphate buffer solution

Support: none

References

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