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chitosan-coated doxorubicin-loaded hyaluronic acid-linked β-cyclodextrin conjugate-retinoic acid nanomicelles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

all-trans-retinoic acid

all-trans-retinoic acid trans-retinoic acid retinoic acid tretinoin trans-RA retin A ATRA TRN RA
Type Single Compound
Formula C20H28O2
Role core
2

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
3

hyaluronic acid-linked β-cyclodextrin conjugate

HA-CD
Type Biomolecule
Formula
Role layer
4

chitosan

CS
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Wistar rat

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. vOt9beMhkdndhkiArij3DaL4CBPNtyiFt
Product

chitosan-coated doxorubicin-loaded hyaluronic acid-linked β-cyclodextrin conjugate-retinoic acid nanomicelles

Size: 204.297 - 208.503 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. 3YjAaAS3KMnNJCPaziEZgYTPskEJZ47ie
Product

chitosan-coated doxorubicin-loaded hyaluronic acid-linked β-cyclodextrin conjugate-retinoic acid nanomicelles

Size: 199.08 - 205.92 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. uxYq2ot9C6z0U3mIPrMGBZwaKOtzWa0Ey
Product

chitosan-coated doxorubicin-loaded hyaluronic acid-linked β-cyclodextrin conjugate-retinoic acid nanomicelles

Size: 185.13 - 189.47 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. HPlkwGN6eXVfKfrtlTHZ5LdxWpc0XpAWX
Product

chitosan-coated doxorubicin-loaded hyaluronic acid-linked β-cyclodextrin conjugate-retinoic acid nanomicelles

Size: > 100 - ~ 500 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. 5yv70Rn8GPJTM9iWyjP9KOQWqSIcwG2t8
Product

chitosan-coated doxorubicin-loaded hyaluronic acid-linked β-cyclodextrin conjugate-retinoic acid nanomicelles

Size: 248.68 - 252.12 nm

Medium: water

Support: none

References

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