Loading ...

methotrexate-glycine-tyrosine conjugated O,N-carboxymethyl chitosan nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

methotrexate-glycine-tyrosine conjugated O,N-carboxymethyl chitosan

O,N-CMCS-Gly-Tyr-MTX
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on enzyme type

More information available to subscribers only.

Or, view sample content

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

More information available to subscribers only.

Or, view sample content

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

More information/entries available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Nanomaterial Variant Source
human myeloma RPMI 8226 cells

More information available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • O-carboxymethylated chitosan
  1. UejScEe8jB9uWgt33LK7h4yKOY22M2K0TPqdz0MlrSvCHutLptvGPDwnH8uUr4OK0NZ9h8yOaWHUjqA6xt3bHnXS6jyOPbUXkdbK8
  2. qTXqRK8gmEhUCQLx
  3. Ncp
Product

methotrexate-glycine-tyrosine conjugated O,N-carboxymethyl chitosan nanoparticles

Hydrodynamic diameter: 104 - 106 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • O-carboxymethylated chitosan
  1. 8NjmcAMFvtQRlZgZVHaGiTPuCygl9gLcWZ9mEGYoVKC5VphufFSpfNjqxF1NPVgnQZbZ1YpVa6MgPDCZDEjgYZpZ0A9JbHew8LLWx
  2. fletHylgTspHaRrl
  3. phf
Product

methotrexate-glycine-tyrosine conjugated O,N-carboxymethyl chitosan nanoparticles

Hydrodynamic diameter: 116 - 134 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • O-carboxymethylated chitosan
  1. hBJDrn4r4wL8XSkSBd3K40ZqB2V2mAX7e7567SwlkYhtL4yOXyEZLI7UAw5IUOZGjA2mR9XbNkHtn6rsz079ctUBUudikOrOtctDX
  2. Drsbjon01gar1zrQ
  3. yMy
Product

methotrexate-glycine-tyrosine conjugated O,N-carboxymethyl chitosan nanoparticles

Hydrodynamic diameter: 133 - 135 nm

Medium: phosphate buffer solution

Support: none

References

Full content is available to subscribers only

To view content please choose from the following:

We use cookies to improve your experience with our site. More information

Sign up for a free trial