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docetaxel-loaded PLGA nanoparticles

Based on

1 Articles
2011 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

D-α-tocopheryl polyethylene glycol 1000 succinate

vitamin E TPGS TPGS
Type Polymer
Formula
Role layer
3

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. HgidxDjlYrzWj8ivsfghSIjmimvUxG
Product

docetaxel-loaded PLGA nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. 0A379OTBl6uAJ9ULGjB
Product

docetaxel-loaded PLGA nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. raGeOPvrgyxElrmsFtVv6dUWgIkNEe
Product

docetaxel-loaded PLGA nanoparticles

Method 4

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. o3jjGad5CS0Q69j9jxtWRwDufAg6q5
Product

docetaxel-loaded PLGA nanoparticles

Method 5

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. yptumjsimaGQpZ6n7gWHWtQ3mmky4L
Product

docetaxel-loaded PLGA nanoparticles

References

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