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iloprost-loaded POPC/DOTAP/DPPE-PEG2000 liposomes

Based on

1 Articles
2014 Most recent source

Composition

1

mixture of substance based on (2-amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride/2-amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride/sodium chloride/sodium chloride/water/water)

Type Complex Compound
Formula
Role core
2

iloprost

Type Single Compound
Formula C22H32O4
Role loaded material
3

mixture of substance based on ([(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate/[(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate/[methoxy (polyethyleneglycol)-2000]-dipalmitoylphosphatidylethanolamine/[methoxy (polyethyleneglycol)-2000]-dipalmitoylphosphatidylethanolamine/N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium/N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium)

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human alveolar epithelial A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • [methoxy (polyethyleneglycol)-2000]-dipalmitoylphosphatidylethanolamine
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • iloprost
See all (4)
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Product

iloprost-loaded POPC/DOTAP/DPPE-PEG2000 liposomes

Size: 165.1 - 170.5 nm

Medium: mixture of substance based on (2-amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride/2-amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride/sodium chloride/sodium chloride/water/water)

Support: none

References

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