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gonadorelin-functionalized MION/Mit-loaded liposome

Based on

1 Articles
2014 Most recent source

Composition

1

ammonium sulfate solution

Type Complex Compound
Formula
Role core
2

hydrogenated soybean phosphatidylcholine

hydrogenated soy L-α-phosphatidylcholine hydrogenated soya phosphatidylcholine hydrogenated soy phosphatidylcholine distearoyl phosphatidylcholine distearoylphosphatidylcholine disteroylphosphatidyl choline L-α-phosphatidylcholine Phospholipon® 80H Soy PC HSPC DSPC SPC
Type Single Compound
Formula C44H88NO8P
Role layer
3

N-[carbonyl-methoxy polyethylene glycol 2000]-1,2-distearoyl-sn-glycero-3-phosphorethanolamine sodium salt

PEG2000-DSPE
Type Polymer
Formula
Role layer
4

gonadorelin conjugates with PEG2000-DSPE

gonadorelin-PEG2000-DSPE conjugate gonadorelin-PEG2000-DSPE
Type Complex Compound
Formula
Role layer
5

magnetic iron oxide nanoparticles

Fe3O4 nanoparticles MION
Type Nano Material
Formula
Role loaded material
6

1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione

1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino) ethylamino]-anthracene-9,10-dione mitoxantrone mitox MTX MTO Mit
Type Single Compound
Formula C22H28N4O6
Role loaded material
7

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
mitoxantrone release

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast cancer cells MCF-7

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

gonadorelin-functionalized MION/Mit-loaded liposome

Size: 135.16 - 137.04 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. WL7q15K
Product

gonadorelin-functionalized MION/Mit-loaded liposome

Size: not specified

Medium/Support: none

References

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