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temozolomide-loaded mesoporous silica nanoparticles

Based on

2 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

polybutylcyanoacrylate

PBCA
Type Polymer
Formula
Role carriers
2

3,4-dihydro-3-methyl-4-oxoimidazo [5,1-d]-as-tetrazine-8-carboxamide

8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4-(3H)-one temozolomide TMZ
Type Single Compound
Formula C6H6N6O2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
C6 glioma Rattus norvegicus brain glioma cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. ZeBQKGY6Oow5nk1lo1
Product

temozolomide-loaded mesoporous silica nanoparticles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 3,4-dihydro-3-methyl-4-oxoimidazo [5,1-d]-as-tetrazine-8-carboxamide
  • butyl ester of 2-cyano-2-propenoic acid
  1. 3lnly13PK1Z2GIkM4n4ewyK9epa43fjNDpUP5W8rgGgr3DQulmWf1Iqxrx4bWN69hfh5U1mHU
Product

temozolomide-loaded mesoporous silica nanoparticles

Size: not specified

Medium: saline

Support: none

References

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