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pranlukast hemihydrate-loaded self-microemulsifying drug-delivery system

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

SMEDDS formulation

Type Complex Compound
Formula
Role core
2

SMEDDS layer formulation

Type Complex Compound
Formula
Role layer
3

pranlukast hemihydrate

Onon® PLH
Type Single Compound
Formula C54H48N10O9
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on Tween 80 concentration

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polyoxyethylene (20) sorbitan monolaurate
  • simulated intestinal fluid
  • triethanol amine
See all (6)
  1. qNUfR9S
Product

pranlukast hemihydrate-loaded self-microemulsifying drug-delivery system

Hydrodynamic diameter: 6.30 - 6.80 nm

Medium: simulated intestinal fluid

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • polyoxyethylene (20) sorbitan monolaurate
  • water
  • triethanol amine
See all (6)
  1. COlWdVe
Product

pranlukast hemihydrate-loaded self-microemulsifying drug-delivery system

Hydrodynamic diameter: 1.35 - 1.79 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • polyoxyethylene (20) sorbitan monolaurate
  • triethanol amine
  • phosphate buffer solution
See all (6)
  1. lt400lB
Product

pranlukast hemihydrate-loaded self-microemulsifying drug-delivery system

Hydrodynamic diameter: 9.40 - 10.02 nm

Medium: phosphate buffer solution

Support: none

References

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