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[125I-labeled] Den-RGD-Angio nanoprobe

Based on

1 Articles
2012 Most recent source

Composition

1

poly(amidoamine) dendrimer

PAMAM G5 dendrimer PAMAM-G5
Type Polymer
Formula
Role core
2

Mal-PEG2K-NHS

Type Polymer
Formula
Role layer
3

c[RGDyK] peptide

Type Biomolecule
Formula
Role layer
4

cyanine 5.5

Cy5.5
Type Single Compound
Formula C40H46N2O5P1+
Role layer
5

9-(2-carboxyphenyl)-6-(diethylamino)-N,N-diethyl-3H-xanthen-3-iminium chloride

Rhodamine 610 Rhodamine B rhodamine B rhodamine-B Rhodamine rhodamine Rh 610 Rho B Rho-B RhoB Rhod RDB RhB Rho RB
Type Single Compound
Formula C28H31ClN2O3
Role layer
6

poly (N-succinimidyl 3-maleimidopropionate/N-succinimidyl 3-maleimidopropionate/dimethylene oxide/dimethylene oxide/C9H11N2OS2-/C9H11N2OS2-)

Type Polymer
Formula
Role layer
7

cysteine modified Angiopep-2 peptide

Type Biomolecule
Formula
Role layer
8

125I-labeled Bolton-Hunter Reagent

Type Complex Compound
Formula
Role layer
9

Gd3+-DOTA

DOTA-Gd
Type Single Compound
Formula GdC16H25N4O8
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
U87MG tumor-bearing Balb/c mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
Product

[125I-labeled] Den-RGD-Angio nanoprobe

Size: not specified

Medium/Support: none

References

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