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thermo-sensitive liposomes loaded with doxorubicin and lysine modified single-walled carbon nanotubes

Based on

1 Articles
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

mixture of substance based on (1,2-dipalmitoyl-sn-glycero-phosphatidylcholine/1,2-dipalmitoyl-sn-glycero-phosphatidylcholine/cholesteryl hemisuccinate/cholesteryl hemisuccinate/DSPE-PEG2000/DSPE-PEG2000)

Type Complex Compound
Formula
Role layer
3

Lysine-modified SWNT

Lys/SWNT
Type Nano Material
Formula
Role loaded material
4

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on temperature

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
S180 tumor-bearing mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • cholesteryl hemisuccinate
  • DSPE-PEG2000
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
  1. Y0mGqH9xED
Product

thermo-sensitive liposomes loaded with doxorubicin and lysine modified single-walled carbon nanotubes

Size: ~ 200 nm

Medium/Support: none

References

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