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poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Based on

1 Patents
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

acetylated carboxymethylcellulose

CMC-Ac
Type Biomolecule
Formula
Role raw materials
2

poly(ethylene glycol) methyl ether

mPEG-OH
Type Polymer
Formula
Role graft
3

cabazitaxel

CABA CBZ CTX
Type Single Compound
Formula C45H57NO14
Role loaded material

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cancer associated fibroblasts

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. xNkz9fxD6IdPccqLkK2Gj2K7ZplGf
  2. 03BiuzISG6puspRYzxWya9E7cTEr4nOqpZzQTZoWJOBGDCxILfP9g0f5x0wsnY4Oh27rno
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 112 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. YACUJMXcie9beEl1w4vonihDOP73S
  2. qAOfPJiLaDM13VWlutKSKRYpPSId6owVEGJFZpRrFZA21vyQscrhn4h3WYkk2coahzDx5H
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 47.82 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. haB9J6ATXhRMoAyM49GJhJ9WCwL2I
  2. uOgrIaP3wWnGvCCJZ2MepfFwlan15NlSBcjYpDubMZH6qjfMCCzhfnlXt523vHMSLN8FUV
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 54.36 nm

Medium: water

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. M3Tplg2QupisF0Ndi7cdgoi7Yyy8H
  2. RogdeNlxKlZfBScZtanuDBC3w2WbfxszJ3UupccFtK6foqX436dFFS43nFdhRxKh0cgfmv
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 45.96 nm

Medium: water

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. 9hWb53H6OgAfYZimBTyYurRTKUVDS
  2. vspoHeoepFiXOBDTUzqxjifX5D60h3QtMQKNl79Un6lGDrcgh27IT8I11livS6MTOAqCdk
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 69.21 nm

Medium: water

Support: none

References

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