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bolaamphiphilic nanovesicle

Based on

2 Patents
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

[2-(acetyloxy)ethyl](2-{[(9E)-18-[(10-{[(9E)-13-[(2-{[2-(acetyloxy)ethyl]dimethylazaniumyl}acetyl)oxy]-12-hydroxyoctadec-9-enoyl]oxy}decyl)oxy]-7-hydroxy-18-oxooctadec-9-en-6-yl]oxy}-2-oxoethyl)dimethylazanium dichloride

bolaamphiphilic compound GLH-20
Type Single Compound
Formula C62H114Cl2N2O14
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • [2-(acetyloxy)ethyl](2-{[(9E)-18-[(10-{[(9E)-13-[(2-{[2-(acetyloxy)ethyl]dimethylazaniumyl}acetyl)oxy]-12-hydroxyoctadec-9-enoyl]oxy}decyl)oxy]-7-hydroxy-18-oxooctadec-9-en-6-yl]oxy}-2-oxoethyl)dimethylazanium dichloride
  1. kdn9oNr0Ej
Product

bolaamphiphilic nanovesicle

Hydrodynamic diameter: ~ 90 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • [2-(acetyloxy)ethyl](2-{[(9E)-18-[(10-{[(9E)-13-[(2-{[2-(acetyloxy)ethyl]dimethylazaniumyl}acetyl)oxy]-12-hydroxyoctadec-9-enoyl]oxy}decyl)oxy]-7-hydroxy-18-oxooctadec-9-en-6-yl]oxy}-2-oxoethyl)dimethylazanium dichloride
  1. 2k6D0g9dJJ
Product

bolaamphiphilic nanovesicle

Diameter: 50 - 300 nm

Hydrodynamic diameter: ~ 368 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • [2-(acetyloxy)ethyl](2-{[(9E)-18-[(10-{[(9E)-13-[(2-{[2-(acetyloxy)ethyl]dimethylazaniumyl}acetyl)oxy]-12-hydroxyoctadec-9-enoyl]oxy}decyl)oxy]-7-hydroxy-18-oxooctadec-9-en-6-yl]oxy}-2-oxoethyl)dimethylazanium dichloride
  1. q1g7RyGbpB
Product

bolaamphiphilic nanovesicle

Hydrodynamic diameter: ~ 90 nm

Size: ~ 50 - ~ 110 nm

Medium: phosphate buffer solution

Support: none

References

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