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bolaamphiphilic nanovesicle

Based on

3 Patents
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

bolaamphiphilic compound-lipid mixture

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • {2-[(5-{[(9E)-7-hydroxy-17-({11-[(9E)-12-hydroxy-13-({5-oxo-5-[2-(trimethylazaniumyl)ethoxy]pentanoyl}oxy)octadec-9-enamido]undecyl}carbamoyl)heptadec-9-en-6-yl]oxy}-5-oxopentanoyl)oxy]ethyl}trimethylazanium dichloride
  • cholesteryl hemisuccinate
  1. aZguYkscPH
Product

bolaamphiphilic nanovesicle

Diameter: 50 - 120 nm

Hydrodynamic diameter: 99.9 - 101.7 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • {2-[(5-{[(9E)-7-hydroxy-17-({11-[(9E)-12-hydroxy-13-({5-oxo-5-[2-(trimethylazaniumyl)ethoxy]pentanoyl}oxy)octadec-9-enamido]undecyl}carbamoyl)heptadec-9-en-6-yl]oxy}-5-oxopentanoyl)oxy]ethyl}trimethylazanium dichloride
  • cholesteryl hemisuccinate
  1. V0x7XkxzBU
Product

bolaamphiphilic nanovesicle

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • {2-[(5-{[(9E)-7-hydroxy-17-({11-[(9E)-12-hydroxy-13-({5-oxo-5-[2-(trimethylazaniumyl)ethoxy]pentanoyl}oxy)octadec-9-enamido]undecyl}carbamoyl)heptadec-9-en-6-yl]oxy}-5-oxopentanoyl)oxy]ethyl}trimethylazanium dichloride
  • cholesteryl hemisuccinate
  1. qfSv9NEI1p
  2. JkdQxR8
Product

bolaamphiphilic nanovesicle

Hydrodynamic diameter: 94 - 160 nm

Medium: phosphate buffer solution

Support: none

References

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