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doxorubicin-loaded polyethylenimine-enhanced human serum albumin nanoparticles

Based on

72 Articles
2017 Most recent source

Composition

1

FITC-labeled cRGD-poly(ethylene glycol)-b-[poly(2,4,6-trimethoxybenzylidene-1,1,1-tris(hydroxymethyl)ethane methacrylate-co-2-aminoethyl methacrylate)] nanosized micelles

FITC-labeled cRGD-PEG45-b-P(TTMA-co-MAA) nanosized micelles cRGD-PETM-FITC nanosized micelles
Type Nano Material
Formula
Role carriers
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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drug release dependent on pH
Zeta potential

Applications

Area Application Nanomaterial Variant Source
drug delivery

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medicine/veterinary

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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fluorescence spectroscopy
transmission electron microscopy
UV
UV-Vis spectroscopy

Biological effects

Biological system Test details Nanomaterial Variant Source
HeLa cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • adriblastin
  • methoxy poly(ethylene glycol)-b-poly(5-allyloxy-1,3-dioxan-2-one)
  1. kqk
  2. OFLDDcVEi0V2B
  3. wFu
  4. wZvwKLhQn4gKOSF
  5. vpY
Product

doxorubicin-loaded polyethylenimine-enhanced human serum albumin nanoparticles

Diameter: 48 nm

Hydrodynamic diameter: 56.5 - 62.9 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • butanedioic acid
  • glucosamine
  1. vKa66FcJssaUKgETFDNWmA20H4qDRwsPnC
  2. IYrLmkMORQ0aX
Product

doxorubicin-loaded polyethylenimine-enhanced human serum albumin nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • hyaluronic acid-cystamine-polylactic-co-glycolic acid
  1. oShz69snOyOFoe7ZEdrDsvFGU1
Product

doxorubicin-loaded polyethylenimine-enhanced human serum albumin nanoparticles

Hydrodynamic diameter: 207.7 - 212.5 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
  1. Ls3
Product

doxorubicin-loaded polyethylenimine-enhanced human serum albumin nanoparticles

Size: 300.27 - 365.07 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • dextran-poly(DL-lactide-co-glycolide) block-copolymer
  • adriblastin
  1. aYzVci4VotOXaeLxxM
  2. UXxDYWK3DmDUF
  3. pGMXhyrzTVFUkQQP
Product

doxorubicin-loaded polyethylenimine-enhanced human serum albumin nanoparticles

Size: 160.2 - 206.5 nm

Medium: water

Support: none

References

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