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zidovudine solid lipid nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

3'-azido-3'-deoxythymidine

zidovudine AZT
Type Single Compound
Formula C10H13N5O4
Role core
2

octadecanoic acid

stearic acid SA
Type Single Compound
Formula C18H36O2
Role layer
3

poly(vinyl alcohol)

polyvinyl alcohol PVOH PVAI PVA
Type Polymer
Formula
Role layer
4

polyoxyethylene (20) sorbitan monooleate

Polysorbate 80 Alkest TW 80 Tween 80
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Charles Foster strain albino rat

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • water
  • 3'-azido-3'-deoxythymidine
  • polyoxyethylene (20) sorbitan monooleate
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Product

zidovudine solid lipid nanoparticles

Hydrodynamic diameter: 600 - 630 nm

Medium: water

Support: none

References

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