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anti-EGFR antibody and Cy5.5 dye labeled Fe3O4 nanocrystals

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

iron(II,III) oxide

magnetite
Type Single Compound
Formula Fe3O4
Role core
2

polyethylene glycol

HOOC-PEG-COOH
Type Polymer
Formula
Role layer
3

anti-epidermal growth factor receptor antibody labeled with Cy5.5 dye

Cy5.5 labeled anti-EGFR antibody anti-EGFR-Cy5.5
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
fluorescence spectroscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c-nude mouse bearing MDA-MB-231 cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. KodsHS4ttnVm
Product

anti-EGFR antibody and Cy5.5 dye labeled Fe3O4 nanocrystals

Size: ~ 14 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
  1. vA7LqKgoIAkZ
  2. WQLCPvVDT7cb3fP4VPSMH4JjzRoLaAgaJrsJ3RDGPoz64jw6qxFNL0UvmjxqTZ4Q0C0j4QrXrSLJB8ABsA5YM2pAFx0vOJQB3V1603QW3gOvBOBWV8vXnJ43RvlP7C3g
Product

anti-EGFR antibody and Cy5.5 dye labeled Fe3O4 nanocrystals

Size: ~ 14 nm

Medium: phosphate buffered saline

Support: none

References

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