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camptothecin-loaded methoxy poly(ethylene glycol)-block-polyacrylate-graft-poly(N-isopropylacrylamide) nanomicelles

Based on

1 Articles
2014 Most recent source

Composition

1

(S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione

1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione (S)-(+)-camptothecin camptothecin CPT CMT CP
Type Single Compound
Formula C20H16N2O4
Role core
2

methoxy poly(ethylene glycol)-block-polyacrylate-graft-poly(N-isopropylacrylamide)

mPEG45-b-PA-g-PNIPAM11 comb block copolymer
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
human breast cancer MDA-MB231 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • methoxy poly(ethylene glycol)-block-polyacrylate-graft-poly(N-isopropylacrylamide)
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  1. WKl58AZQcfsx95q
Product

camptothecin-loaded methoxy poly(ethylene glycol)-block-polyacrylate-graft-poly(N-isopropylacrylamide) nanomicelles

Method 2

Type: Physical formation
Source:
  1. g8JTv6ziy4KudAvuOIHdlTYYOunoqfKpIGs
  2. GwSr4RqyNiOY0yAphOBIez3U9drC
Product

camptothecin-loaded methoxy poly(ethylene glycol)-block-polyacrylate-graft-poly(N-isopropylacrylamide) nanomicelles

References

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