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oxaliplatin-loaded hyaluronic acid-coupled chitosan tripolyphosphate nanoparticles

Based on

1 Articles
2010 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

chitosan

Type Biomolecule
Formula
Role carriers
2

tripolyphosphate anion

tripolyphosphate TPP anion TPP
Type Single Compound
Formula P3O105-
Role fillers
3

hyaluronic acid

HA
Type Biomolecule
Formula
Role graft
4

[oxalato(l-trans-1,2-diaminocyclohexane)]platinum(II)

oxaliplatin eloxatin elplat L-OHP OXA Oxa
Type Single Compound
Formula C8H14N2O4Pt
Role loaded material

Properties

General physical and chemical properties

Property Value Source
in-vitro oxaliplatin release from nanoparticle-encapsulating enterically protected pellet

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
C57BL mouse with human colon cancer HT-29 cells (colon mucosa)

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
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  2. vk7sSMFxsOX9MPvZi5GcpZCFdZbd0hMcxgiEwpGqRu6xUVazExoa9K4fNcsZg5
  3. ImjquMIFwMYdu9
  4. mqsZiywMeOaDr1
Product

oxaliplatin-loaded hyaluronic acid-coupled chitosan tripolyphosphate nanoparticles

References

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