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5% DMAB-modified docetaxel-loaded PLGA nanoparticles

Based on

1 Articles
2011 Most recent source

Composition

1

poly(lactide-co-glycolide)

PLGA
Type Polymer
Formula
Role carriers
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material
3

N-dodecyl-N,N-dimethyldodecan-1-aminium bromide

dodecyl-N,N-dimethyl-1-dodecanaminium bromide didodecyl dimethylammonium bromide didodecyldimethylammonium bromide dimethyldidodecylammonium bromide dilauryldimethylammonium bromide dDDdMABr DDAB DMAB
Type Single Compound
Formula C26H56BrN
Role layer

Properties

General physical and chemical properties

Property Value Source
biodegradability

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
MCF-7 cancer cell

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • poly(lactide-co-glycolide)
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. 4DhPFV1uApe2Xvzk9RE8X7juNr
Product

5% DMAB-modified docetaxel-loaded PLGA nanoparticles

References

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