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transferrin-conjugated temozolomide-loaded solid lipid nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

1

mixture of substance based on (3,4-dihydro-3-methyl-4-oxoimidazo [5,1-d]-as-tetrazine-8-carboxamide/3,4-dihydro-3-methyl-4-oxoimidazo [5,1-d]-as-tetrazine-8-carboxamide/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine/1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine/soya phosphatidylcholine/soya phosphatidylcholine/glycerol trioleate/glycerol trioleate/cholesterol/cholesterol)

Type Complex Compound
Formula
Role core
2

transferrin

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
scanning electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
CNS cancer U373-MG cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. dOa
  2. YTHSrxVJn9VNNjzOQbjmCDUQUKH1LO7yi52qBA7SL4qnsCU3qaIGAPWe8dQ
  3. sC9mag4Lp
Product

transferrin-conjugated temozolomide-loaded solid lipid nanoparticles

Size: 246.4 - 251.6 nm

Medium: phosphate buffer saline

Support: none

References

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