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docetaxel-encapsulated chitosan-modified PLGA nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

1

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role core
2

poly(lactic-co-glycolic acid)

poly lactic-co-glycolic acid PLGA
Type Polymer
Formula
Role layer
3

chitosan

CS
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
blood of Wistar rat

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. jZSys0HT7Md6srX9o6RaPbTYIh813brjs3QDYl6KuYf7J1Kjqc
Product

docetaxel-encapsulated chitosan-modified PLGA nanoparticles

Size: not specified

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. EJcAkGb2PotOBJcaZoDfvWYfiu5gR86SfKfZfzrVnSLsBdIml
Product

docetaxel-encapsulated chitosan-modified PLGA nanoparticles

Size: not specified

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. tycqFxqcnhmedXEGP3d1SiPjXhXqSYTK2F73ajyXmqb8q6HTj
Product

docetaxel-encapsulated chitosan-modified PLGA nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. VO2iEzVPWZijyhpc16vrWXg5hbscQYsXzAoEjKaYTNl3Xszud
Product

docetaxel-encapsulated chitosan-modified PLGA nanoparticles

Size: not specified

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • chitosan
  1. YTdI7VIE14RTX2pC8ooddvo0oRXHB3EvwQxx5ubSQpgq2K6PR
Product

docetaxel-encapsulated chitosan-modified PLGA nanoparticles

Hydrodynamic diameter: ~ 233.38 - ~ 252.22 nm

Medium: water

Support: none

References

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