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propofol-loaded mPEG-PLA/Solutol HS15 mixed micelles

Based on

1 Articles
2011 Most recent source

Composition

1

methoxy poly(ethylene glycol)-b-poly(d,l-lactide) diblock copolymers

mPEG-PLA diblock copolymer mPEG5000-PLA4800 copolymer mPEG-PLA
Type Polymer
Formula
Role raw materials
2

polyethylene glycol 660 ester of 12-hydroxystearic acid

polyoxyethylene-660-12-hydroxystearate Solutol HS15
Type Polymer
Formula
Role core
3

2,6-diisopropylphenol

propofol
Type Single Compound
Formula C12H18O
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
propofol release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Sprague-Dawley rat

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • polyethylene glycol 660 ester of 12-hydroxystearic acid
  • methoxy poly(ethylene glycol)-b-poly(d,l-lactide) diblock copolymers
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  2. Cz3xoS
  3. EcDg
Product

propofol-loaded mPEG-PLA/Solutol HS15 mixed micelles

Size: 88.0 - 123.2 nm

Medium: water

Support: none

References

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