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docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Based on

1 Articles
2013 Most recent source

Composition

1

5.0 G polypropylenimine dendrimer-polyethylene glycol 6000-folate nanoconjugate

folate-conjugated 5.0 G polypropylenimine dendrimer PPI dendrimer-based folate-anchored nanoconjugate folate-PEG6000-5.0 G PPI nanoconjugate folate-conjugated 5.0 G PPI dendrimer PPI-folate nanoconjugate folate-PPI nanoconjugate PPIFA nanoconjugate PPI-PEG6000-Folate PPI-Folate PPIP6FA PPIFA
Type Nano Material
Formula
Role carriers
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
in vitro drug release profile of DTX dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
estrogen receptor-positive human breast cancer MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. t4Pf0uNQC2O9YEMqUqh22mgkbHfb6Fnnwn0Onysn0FRapYV
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. PzfYmJQvNglcmLis8Xivji52MApztfyAcgEfQ4ypG2bGXXt
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  1. xosmpSrPaYF82ZJlkcEfENu093c9jewqnnWrALLjfVFNqbk
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  1. qwxLNeFLPbIXwhgzVpRY5PmmuK7CphfBol3pUHPMcXbYsEo
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  1. VJQeqGTIPQuJrvpIonYgloEGdMuAUlkl83jouoqxd4VNFGc
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

References

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