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vismodegib-loaded nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

methoxy-polyethylene-glycol-b-poly(carbonate-co-lactide)

mPEG-b-p(CB-co-LA) copolymer mPEG114-b-p(CB55-co-LA160) mPEG-b-p(CB-co-LA)
Type Polymer
Formula
Role carriers
2

vismodegib

GDC-0449 GDC VIS
Type Single Compound
Formula C19H14Cl2N2O3S
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
cumulative drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
male Sprague Dawley rats

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • vismodegib
  • methoxy-polyethylene-glycol-b-poly(carbonate-co-lactide)
  1. M2MghHfrLyWxrxfgkTqRtCf7t0lOLEFWbwB5dFFZq6S
Product

vismodegib-loaded nanoparticles

Size: not specified

Medium/Support: none

References

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