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paclitaxel-loaded methoxypolyethylene glycol-poly(DL-lactide) diblock copolymer nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(DL-lactide)

PLA
Type Polymer
Formula
Role binder
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PCL PAC PTX PX
Type Single Compound
Formula C47H51NO14
Role dopant
3

methoxy poly(ethylene glycol)

MPEG
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • methoxypolyethylene glycol-poly(DL-lactide) diblock copolymer
  • Paclitaxel
  1. LjJ5O1G
  2. G0JA8
Product

paclitaxel-loaded methoxypolyethylene glycol-poly(DL-lactide) diblock copolymer nanoparticles

Size: ~ 100 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • methoxypolyethylene glycol-poly(DL-lactide) diblock copolymer
  • Paclitaxel
  1. UmOzWTW
  2. G3HZk
Product

paclitaxel-loaded methoxypolyethylene glycol-poly(DL-lactide) diblock copolymer nanoparticles

Hydrodynamic size: 179.5 nm

Medium: water

Support: none

References

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