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doxorubicin hydrochloride water dispersion encapsulated folic acid conjugated polyhedral oligomeric silsesquioxane - Pluronic F68 hybrid vesicles

Based on

1 Articles
2014 Most recent source

Composition

1

doxorubicin hydrochloride dispersion in water

Type Complex Compound
Formula
Role core
2

poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer

Pluronic F68
Type Polymer
Formula
Role layer
3

amino- and vinyl-functionalized polyhedral oligomeric silsesquioxane

Type Complex Compound
Formula
Role layer
4

poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer

Pluronic F68
Type Polymer
Formula
Role layer
5

folate acid

folic acid folate FOL FA
Type Single Compound
Formula C19H19N7O6
Role layer

Properties

General physical and chemical properties

Property Value Source
doxorubicin release profile dependent on pH

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
scanning electron microscopy

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Biological effects

Biological system Test details Source
human cervical cancer HeLa cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 3-aminopropyltriethoxysilane
  • triethoxysilylethylene
  1. nTjXgbAKrh9Iww0SG8mtWq
Product

doxorubicin hydrochloride water dispersion encapsulated folic acid conjugated polyhedral oligomeric silsesquioxane - Pluronic F68 hybrid vesicles

References

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