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PEG-peptide-DOPE-MEND

Based on

1 Articles
2011 Most recent source

Composition

1

siRNA/STR-R8 complex

Type Complex Compound
Formula
Role core
2

(2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphatidyl-ethanolamine 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleyl-sn-glycerophosphoethanolamine dioleoyl-phosphatidyl ethanolamine dioleoyl-phosphatidylethanol-amine dioleoylphosphatidylethanolamine DOPA DOPE
Type Single Compound
Formula C41H78NO8P
Role layer
3

peptide

Type Biomolecule
Formula
Role layer
4

distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

PEG2k-DSPE
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
HT1080 cell stably expressing luciferase

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • peptide
  1. gnr9u18SNRwcvYIOjfIYMpcKn4HGL1yOn1GlR1wIxZ0ehSHyBqfw5kW7h8smlvMwcOkR2shW2wVhUa0dz6hv
Product

PEG-peptide-DOPE-MEND

Method 2

Type: Physical formation
Source:
Starting materials
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • peptide
  1. 4eIKr73HYu0bA1jv8yKJly7wBlQMpLebzKlCfiJqV5Zy2Dq8KEfEhDpikhApXleMjr2LLlwwW5I6EwlnHzhX
Product

PEG-peptide-DOPE-MEND

References

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