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PEG-peptide-DOPE-MEND

Based on

1 Articles
2011 Most recent source

Composition

1

siRNA/STR-R8 complex

Type Complex Compound
Formula
Role core
2

(2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphatidyl-ethanolamine 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine 1,2-dioleyl-sn-glycerophosphoethanolamine dioleoyl-phosphatidyl ethanolamine dioleoyl-phosphatidylethanol-amine dioleoylphosphatidylethanolamine DOPA DOPE
Type Single Compound
Formula C41H78NO8P
Role layer
3

peptide

Type Biomolecule
Formula
Role layer
4

distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

PEG5k-DSPE
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
HT1080 cell stably expressing luciferase

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • peptide
  1. oQw3OPu72GqnlOVj9b6q4s6ZzW1jElF5MaQhc7mDqxkMuRmV7q8JlpnP7DdzL33VDimk6H0WUK5OLj3oafCc
Product

PEG-peptide-DOPE-MEND

Diameter: 94 - 111 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (2-aminoethoxy)({2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy})phosphinic acid
  • distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • peptide
  1. 06qrQXSc2700J4N7ZAATKHr3ScOBx8qnoGb0iUDdHQBUBohm74zeoBol9WmeGxHSFKMX8byCO7eCCGanLuK8
Product

PEG-peptide-DOPE-MEND

Diameter: 89 - 134 nm

Medium/Support: none

References

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