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paclitaxel-loaded Angiopep-conjugated PEG-PCL nanoparticles

Based on

1 Articles
2011 Most recent source

Composition

1

poly(ethylene glycol)-co-poly(ε-caprolactone)

PEG-PCL
Type Polymer
Formula
Role core
2

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

methoxy terminus

methoxy moiety methoxy group methoxy
Type Single Compound
Formula -OCH3
Role layer
4

maleimide residue

maleimide moiety maleimide group maleimide
Type Single Compound
Formula -C4H2NO2
Role layer
5

Angiopep-2

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
brain capillary endothelial cell

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. ZnX1nJkPC8iE0yJnaHD8I
  2. s7IJ0zC54hgcN
Product

paclitaxel-loaded Angiopep-conjugated PEG-PCL nanoparticles

Diameter: ~ 20 - ~ 300 nm

Medium/Support: none

References

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