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paclitaxel-topotecan containing liposomes

Based on

1 Articles
2013 Most recent source

Composition

1

mixture of substance based on (phosphate buffer/topotecan)

Type Complex Compound
Formula
Role core
2

mixture of substance based on (monomethoxy PEG 2000-distearoyl phosphatidylethanolamine/1,2-Dimyristoyl-sn-glycero-3-phospho-(1-rac-glycerol)/1,2-dipalmitoyl-sn-glycero-phosphatidylcholine)

Type Complex Compound
Formula
Role layer
3

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on pH

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
differential centrifugal sedimentation

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Biological effects

Biological system Test details Source
OVCAR-3 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • mixture of substance based on (folate acid moiety/-C45H85NO10P/polymer)
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
  • monomethoxy PEG 2000-distearoyl phosphatidylethanolamine
See all (5)
  1. wPQaw3RoPz
  2. NIpOpsMD
Product

paclitaxel-topotecan containing liposomes

References

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